Hellsing, an organization devoted to the elimination of the vampire threat, has recently uncovered information regarding the attempted production of "man-made" undead. The world is presently in the thick of WWII, and the current leader of Hellsing fears the Nazis could potentially use these creatures as front-line super-soldiers. Although the technology of creating artificial vampires is still in its infancy, it has advanced enough to be a serious threat. In an attempt to put a stop to this perverse and dangerous experimentation, Hellsing has sent two of its most skillful agents to Poland. A young man by the name of Walter C. Dornes - a.k.a. "The Angel of Death," and Alucard, an ancient vampire currently in forced service to the Hellsing Organization. Together, they attempt to stop the progress of the Nazi's efforts.