Knights is a shounen manga tale about squire Mistletien, called 'Mist' for short. Taking place in a medieval world in which the church and her representatives are burning people en masse on suspicion of witchcraft, Mist and his organization are taking a stand against the church and the 'Saints' who are perpetuating the witch hunts. Mist is feared and hated by the village-folk because of his appearence, wearing a mask to disguise himself and going by the moniker 'The Black Knight.' He travels with Euphemia, a young girl who is as expert with mixing potions and poisons as Mist is with a sword, and together they rescue those who are to be executed on suspicion of witchcraft.