Sasafune Miyoko, the nurse at a certain high school, is often asked for advice by the students. Almost every day someone comes to ask her about their worries, and this and that... But since these are high school students going through puberty, helping them is usually not that simple! Myou-chan-sensei is hard at work answering questions that are sure to make you blush like "Have you ever had sex outdoors?" or "I wonder which panties my boyfriend likes more".