A special tonic found among Rome's ancient catacombs is consumed by three stray puppies, giving them incredible powers of super strength, amazing intelligence and lightning speed. These three dogs - Ben, Uru and Puchi - swear to defend a boy who has a map of a hidden treasure in the Silk Road, all while fighting against evil organizations and even competing with one another to help their master.

Volumes 180-182 of the Osamu Tezuka Complete Works